Eye development: Governed by a dictator or a junta?
Article Abstract:
Imaginal discs, the structures giving rising to the eyes of the adult fly use the same morphogenetic molecules. The ability of genes to induce ectopic eyes provides a model of regulation for eye development, in Drosophila and in vertebrates. Pax6 in the eye. eyless (ey) is the gene encoding the Drosophila Pax6 homolog, and is essential for eye development. It is thought that downstream genes can induce ectopic eyes. dac or eya alone.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
The origins of polypeptide domains
Article Abstract:
Two models of the origin of novel polypeptide domains are proposed, based on 'exonization' of intron sequences and insertion-based polymorphisms between orthologous genes. These processes are discussed, also analyzing how each might participate in the evolutionary emergence of novel polypeptide domains.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: The homeodomain: a new face for the helix-turn-helix? The management of DNA double-strand breaks in mitotic [G.sub.2], and in mammalian meiosis viewed from a mitotic [G.sub.2] perspective
- Abstracts: The rel family of proteins. The end of the message: 3'-end processing leading to polyadenylated messenger RNA
- Abstracts: Mammalian origins of replication. On the nature of origins of DNA replication in eukaryotes. Accessory protein function in the DNA polymerase III holoenzyme from E. coli