The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism
Article Abstract:
The major cytoplasmic histone acetyltransferase activity of Saccharomyces cerevisiae is biochemically isolated. The two major components of the activity are identified. The first component is shown to encode the catalytic subunit and the second encodes a protein required for high affinity binding of the acetyltransferase to histone H4. The findings provide new information on the acetylation and general metabolism of histones.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta
Article Abstract:
This paper examines telemerase function in the cell by deveeloping an in vivo assay technique. Results show that addition of teleomere by telemerase in vivo is cell cycle-dependent and requires alpha and delta components of DNA polymerases and DNA primase.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
The histone minority report: the variant shall not be silenced
Article Abstract:
This article discusses the role of the histone variant H2A.Z within euchromatin in preventing silent chromatin from migrating to transcriptionally active regions in the chromosome.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo. Telomere-mediated plasmid segregation in Saccharomyces cerevisiae involves gene products required for transcriptional repression at silencers and telomeres
- Abstracts: Molecular cytogenetic evidence for a common breakpoint in the largest inverted duplications of chromosome 15. A Huntington disease-like neurodegenerative disorder maps to chromosome 20p
- Abstracts: Use of cosmid-derived and chromosome-specific canine microsatellites. FISH mapping and identification of canine chromosomes
- Abstracts: The transfer of left-right positional information during chick embryogenesis. Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton
- Abstracts: The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior