The origin and early evolution of life: prebiotic chemistry, the pre-RNA world, and time
Article Abstract:
The discovery of life in the inhospitable temperature environment of submarine vents has led to the inclusion of hyperthermophile research into the origin of life studies. Submarine vents may have been responsible for generating the required organic compounds that led to the development of life forms. The iron sulfide template may have reduced prebiotic compounds to serve as energy sources of organisms. What remains to be resolved is the eventual use of carbon dioxide as an energy source of organisms and the development of polyphosphates as an acceptor in many metabolic pathways.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
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Histidine biosynthetic pathway and genes: structure, regulation, and evolution
Article Abstract:
The histidine (his) biosynthetic pathway is the most studied biochemical pathway since the acceptance of the operon theory. The his pathway has been shown to be present from single cell forms to complex, multi-cell forms. The his genes have been cloned and sequenced in more than 20 species and have been shown to be controlled posttranscriptionally by a system of segmental stabilization of regions in the transcription code.
Publication Name: Microbiological Reviews
Subject: Biological sciences
ISSN: 0146-0749
Year: 1996
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Two genes from Bacillus subtilis under the sole control of the general stress transcription factor sigma(super B)
Article Abstract:
A study was conducted to analyze the range of functions supported by genes controlled by sigma(super B) from Bacillus subtilis. Two csb-lacZ fusions were characterized to carry out the analysis. The premise that the csbC product could support a nutritional or an osmotic protection function was also examined. Results indicated that the sigma(super B) dependent promoter was an internal promoter for the operon.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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