The role of heterochromatin in the expression of a heterochromatic gene, the rolled locus of Drosophila melanogaster
Article Abstract:
Position effects on the heterochromatic rolled gene (rl) and its requirements for a heterochromatic environment were studied through a series of chromosomal rearrangements. Results revealed that rl function is greatly inhibited by rearrangements that isolate it from its normal heterochromatic location near the centromere. However, this effect can be reversed when the gene is moved nearer to a large autosomal or X chromosome heterochromatin block. This indicates that heterochromatic gene function is dependent on its proximity to heterochromatin and suggests that highly repeated satellite DNA is responsible for providing this heterochromatic environment.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1993
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Genetic and environmental effects on the expression of peptidases and larval viability in Drosophila melanogaster
Article Abstract:
The contributions of genetic background and the environment in the expression of enzymes with similar function were assessed. The enzyme system analysed was the peptidase system in Drosophila melanogaster, and genetic and environmental effects were determined on larvae challenged with various levels of osmotic stress. The results showed that genetic variation exists for the peptidase activities, and osmotic stress has variable effects among the peptidases. The variations in peptidase activities depended on both the genetic background and the osmotic effector.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
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The genetic analysis of achiasmate segregation in Drosophila melanogaster. III. The wild-type product of the Axs gene is required for the meiotic segregation of achiasmate homologs
Article Abstract:
Researchers studying the segregational mechanisms concerned with achiasmate chromosomes in Drosophila melanogaster females isolated two intragenic revertants of the aberrant x segregation (AxsD) mutation (Axsr2 and Axsr3) that show a recessive meiotic phenotype identical to the one seen in AxsD/AxsD females. They characterized the interplay of mutations at the Axs locus with two differrent meiotic mutations (ald and ned), and provided a model in which Axz+ is essential for the ordinary separation of paired achiasmate homologs.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1993
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