Thermally regulated translational control of frq mediates aspects of temperature responses in the neurospora circadian clock
Article Abstract:
The effect of temperature on the circadian oscillators was determined using Neurospora strains. Two different forms of FRQ were used to analyze the different physiological aspects of circadian responses and the effect of temperature changes. FRQ level and the rate of protein synthesis increases as the temperature increases. Changes in the temperature can reset the circadian clock as an indirect effect of changing the level of FRQ. Changes in oscillation amplitude is also depndent on temperature changes.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY
Article Abstract:
The effect of translational regulation and time-of-day specific phosphorylation on synthesis of essential clock protein Frequency (FRQ) was established by using the circadian oscillator of Neurospora. Translational initiation sites on the gene frq resulted to two similar but two functionally different forms of FRQ protein. The effects of phosphorylation on the size discrepancy of the two forms of FRQ was determined by the use of immunoprecipitation and Western blot analysis.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
Lessons from the genome sequence of Neurospora crassa: Tracing the path from genomic blueprint to multicellular organism
Article Abstract:
An analysis of over 1,100 of the approximately 10,000 predicted proteins encoded by the genome sequence of the filamentous fungus Neurospora crassa is presented. The basic features of the genome, including the automated assembly, gene calls and global gene analyses are summarized.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Translational control of puf operon expression in Rhodobacter sphaeroides 2.4.1. Isolation of regulatory mutants in photosynthesis gene expression in Rhodobacter sphaeroides 2.4.1 and partial complementation of a PrrB mutant by the HupT histidine-kinase
- Abstracts: Uptake and retention of Vibrio cholerae O1 in the Eastern oyster, Crassostrea virginica. Pulsed-field gel electrophoresis and ribotype profiles of clinical and environmental Vibrio vulnificus isolates
- Abstracts: Antigenic variation in malaria. A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei
- Abstracts: Effects of low temperatures on viability of Cryptosporidium parvum oocysts. Effect of pasteurization on infectivity of Cryptosporidium parvum oocysts in water and milk
- Abstracts: Mechanisms regulating the transport of acetic acid in Saccharomyces cerevisiae. Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid