Two alpha(1-3) glucan synthases with different functions in Aspergillus fumigatus
Article Abstract:
Two AGS genes of Aspergillus fumigatus (AGS1 and AGS2), which are highly homologous to those of Schizosaccharomyces pombe, with different functions are described. In vivo virulence analysis using an original method of mixed infection showed that a 50% reduction in the content of the cell wall alpha(1-3) glucan does not play a significant role in Aspergillus fumigatus pathogenicity and these altered phenotypes are not associated with a modification of virulence.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2005
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Generation and phenotypic characterization of Aspergillus nidulans methylisocitrate lyase deletion mutants: Methylisocitrate inhibits growth and conidiation
Article Abstract:
The propionate metabolism of Aspergillus nidulans was studied to sole the contradiction between carbon source and preservative effect and it revealed the methylcitrate cycle as the responsible pathway. Methylisocirate lyase is one of the key enzymes of the cycle and it catalyzes the cleavage of methylisocitrate into succinate and pyruvate and completes the alpha-oxidation of propionate.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2005
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Construction of a genetically modified wine yeast strain expressing the Aspergillus aculeatus rhaA gene, encoding an alpha-L-Rhamnosidase of enological interest
Article Abstract:
The expression of the gene encoding A. aculeatus RhaA in a commercial wine yeast strain was investigated. The data indicate the biotechnological feasibility of the combination of wine yeast strains producing alpha- L-rhamnosidase of enological relevance.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2003
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