Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif

Article Abstract:

Research describes the formation of a complex between HIV-1 virion infectivity factor, Vif, and the human APOBEC3G, a virion-encapasidated cellular protein that is involved in the deamination of the minus-strand reverse transcript cytosines to uracils, which prevents its virion encapasidation. However, mouse APOBEC3G cannot catalyze encapasidation.

Infection, Retroviruses, HIV antigens, Viroids

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The protein network of HIV budding

Article Abstract:

Research demonstrates that 22 class E proteins along with a protein network consisting of 43 other protein-protein complexes mediate human multivesicular bodies biogenesis as well as participate in the release of HIV and other viruses by budding. Data indicate that AIP1 plays a key role in this viral budding process.

HIV infection, HIV infections, HIV (Viruses), HIV, Lysogeny, Viral antigens

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