What keeps cells in tissues behaving normally in the face of myriad mutations?

Article Abstract:

Many local mutations and large genomic rearrangements per somatic cell, that accumulates with age at different rates per organ, and without visible effects was indicated in the use of a reporter gene in transgenic mice. It was shown that the normalization of the neoplastic phenotype does not require gap junctional communication between cells though transdifferentiation might.

California, Physiological aspects, Genetic aspects, Genetically modified mice

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Detecting functional interactions in a gene and signaling network by time-resolved somatic complementation analysis

Article Abstract:

The complementation of mutational defects in the network mediating stimulus-induced commitment and sporulation of Physarum polycephalum may reflect time-dependent changes in the signaling state of its molecular building blocks. Fusion of two mutant cells and mixing of their cytoplasms conducted a study to investigate the Somatic complementation.

Genetic research, Cytoplasm, Physalaemus pustulosus, Tungara frog

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Magnesium: The missing element in molecular views of cell proliferation control

Article Abstract:

A brief description on specific receptors for growth factors that entrained a protein kinase cascade is presented. The study found a higher frequency of initiation of protein synthesis.

All Other Basic Inorganic Chemical Manufacturing, Industrial inorganic chemicals, not elsewhere classified, Magnesium Compounds, Cell proliferation, Cell research, Cytological research

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