Multiplexed electrical detection of cancer markers with nanowire sensor arrays
Article Abstract:
Highly sensitive, label-free, multiplexed electrical detection of cancer marker is described using silicon-nanowire field-effect devices in which distinct nanowires and surface receptors are incorporated into arrays. Nanowire arrays allowed highly selective and sensitive multiplexed detection of prostate specific antigen (PSA), PSA-alpha 1-antichymotrypsn, carcinoembryonic antigen and mucin-1, including detection to at least 0.9 pg/ml is undiluted serum samples.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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Antibodies cut down to size
Article Abstract:
Researchers have reduced the size of the monoclonal antibodies and have shown that the peptides can deliver a conjugated cytotoxin to tumors with high specificity and that the peptide-toxin fusions have penetrated into the tumor tissues than the parental antibodies.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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Comment about this article or add new information about this topic:
Antibodies cut down to size
Article Abstract:
Researchers have reduced the size of the monoclonal antibodies and have shown that the peptides can deliver a conjugated cytotoxin to tumors with high specificity and that the peptide-toxin fusions have penetrated into the tumor tissues than the parental antibodies.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
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