Illuminating the switch in influenza viruses

Article Abstract:

The requirements for the transition of H5N1, a pathogenic strain of avian flu, to a virulent human pathogen are reviewed. Hemagglutinin proteins need to gain host receptors with an umbrella-like topology.

Analysis, Genetic aspects, Composition, Proteins, Protein structure, Agglutinins, Avian influenza viruses

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High-frequency generation of viable mice from engineered bi-material embryos

Article Abstract:

A new approach for the high-frequency generation of viable mice from engineered bi-material embryos is discussed. These bi-material mice are found to develop into extremely fertile female adults.

Genetic regulation, Animal embryology

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Humanizing mouse thrombi

Article Abstract:

A new mouse model that develops blood clots comprising largely of human platelets is presented. The effect of antiplatelet drugs on human platelets can be evaluated using the mouse model.

Usage, Drug therapy, Heart attack, Blood platelets, Genetically modified mice, Platelet aggregation inhibitors

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