In silico matchmaking
Article Abstract:
Protein Pathways, a Los Angeles-based founded by David Eisenberg and Todd Yeates, developed a computer algorithm that can be used as a prototype for unknown proteins. The method has been used in 4,290 known proteins in Escherichia coli and was able to isolate 6,809 other protein pairs in the bacteria. Similar experiments were performed on yeast.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999
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Genetically targeted chromophore-assisted light inactivation
Article Abstract:
Chromophore-assisted light inactivation (CALI) is the most promising general approach for inactivating specific proteins with high spatial and temporal precision. The use is limited by the need to microinject dye-labeled nonfunction-blocking antibodies.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2003
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Probing the proteasome pathway
Article Abstract:
The 26S proteasome, a very large proteolytic complex, is involved in the degradation of intracellular proteins in eukaryotes.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
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