Lentiviruses to the placental rescue
Article Abstract:
A study reveals that when mouse blastocysts are infected with lentiviral vectors after removal of the zona pellucida, infection is limited to the outermost cells, the trophectoderm which is the precursor of the trophoblast lineage that forms the placental epithelium. The trophectoderm is an effective barrier to lentiviral infection of the inner cell mass which would be of value not only for those wishing to rescue placental mutants but also for those few who are keen to study placental development.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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Towards zoomable multidimensional maps of the cell
Article Abstract:
Emerging methods for representing and visualizing systems data and for achieving semantic zooming or changes in information density while mapping of the cell are described. The metagraph concept seems to most promising for detailed understanding of the protein complexes in cell cycle, displaying modules of metabolism in a hierarchical format and integrating experimental interaction data with structured vocabularies.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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A milestone for endophyte biotechnology
Article Abstract:
Researchers have reported the complete genome sequence of the nitrogen-fixing endophyte, Azoarcus sp. Strain BH72, and compared it to the genomes of the related soil bacterium strain EbN1 and other plant-associated bacteria. Their results clarify the molecular mechanisms that are behind the symbiotic lifestyle of Azoarcus and suggest strategies for applying its nitrogen-fixing abilities in agriculture.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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