Making the most of microarrays
Article Abstract:
MicroArray Quality Control (MAQC) study represents a landmark in DNA microarray research as it provides the community with a thoroughly characterized reference data set against new refinements in platforms and probe sets against which new refinements in platforms and probe sets can be compared. Clinically, it validates the DNA microarray as a tool that is sufficiently robust and reliable to be embraced for use on hard-to-obtain human tissue samples.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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Impact of microarray data quality on genomic data submissions to the FDA
Article Abstract:
The MicroArray Quality Consortium (MAQC) was formed by the US Food and Drug Administration (FDA) in order to create a new set of standards and guidelines for the use of DNA microarray data leading to more effective integration of genomic data in drug development and regulatory assessment. The MAQC program helps in the correct evaluation of voluntary genomic data submissions (VGDS).
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
Article Abstract:
The experimental design and probe mapping efforts that lie behind the MicroArray Quality Consortium (MAQC) project are described and intraplatform consistency across test sites and a high level of interplatform concordance is demonstrated. The results of this study will help in establishing a framework for the use of microarrays in clinical and regulatory settings.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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