New sources of pancreatic beta-cells
Article Abstract:
Two major initiatives are under way to correct the beta-cell deficit of diabetes, of which one would generate beta-cells ex vivo that are suitable for transplantation and the second would stimulate regeneration of beta-cells in the pancreas. Studies show that while beta-cells have a potential for dedifferentiation, expansion, and redifferentiation, the search of new sources of beta-cells has opened new opportunities and spawned clinical trials.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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Production of recombinant protein therapeutics in cultivated mammalian cells
Article Abstract:
Cultivated mammalian cells are used for the production of recombinant proteins for clinical applications because of their capacity for proper protein folding, assembly and post-translational modification. The advancements in production systems as well as through vector and host cell engineering for improving mammalian cell systems are described.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
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ES cells for troubled hearts
Article Abstract:
The significance of the cardiomyocytes derived from human embryonic stem cells in treating the myocardial infarction in an animal is discussed.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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