Optimization of humanized IgGs in glycoengineered Pichia pastoris
Article Abstract:
A study was conducted to demonstrate that human antibodies with specific human N-glycan could be produced in glycoengineered lines of the yeast Pichia pastoris and that generating specific glycoforms could optimize antibody-mediated effector functions. The glycoengineered Pichia pastoris provides a general platform for producing recombinant antibodies with human N-glycosylation.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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Bioartificial organs and acceptable risk
Article Abstract:
Scientists, surgeons and medical researchers in the United States, Switzerland, Canada and Italy discuss risks societally acceptable in surgical transplants, based on demands for artificial organs, biological products, surgical procedure and hormonal deficiency of patients.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999
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