Phosphoproteomics finds itEs timing
Article Abstract:
The temporal dynamics of EGFR signaling has been studied with the help of mass spectrometry. The phosphoproteomics describes a new encoding technique, which allows the comparison of three protein samples, and demonstrates its potential with a comprehensive study of temporal dynamics of epidermal growth factor receptor tyrosine kinase signaling.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
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Towards quantitative analysis of proteome dynamics
Article Abstract:
An innovative strategy called MasterMap is useful for the quantitative analysis of protein-protein interactions based on label-free liquid-chromatography mass spectrometry (LC-MS). The MasterMap approach can be used for charting large-scale interaction networks after extensive multiplexing of biological samples.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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Effects of HER2 overexpression on cell signaling networks governing proliferation and migration
Article Abstract:
The impact of the overexpression of human epidermal growth factor receptor 2 (HER2) on various cell signaling networks is analyzed. Results show that HER2 is extremely beneficial in stimulating proliferation and migration.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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