A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications
Article Abstract:
The yeast two-hybrid system is altered to make possible the detection of protein-protein interactions that necessitates a particular post-translational modification. In spite of the existence of the antagonizing enzyme activities, the catalysis still sustains the alterations made to the substrate.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
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Protein-protein interaction networks and biology-what's the connection?
Article Abstract:
The problems associated with data handling protocols and biases in protein-protein interaction (PPI) networks analysis are presented. Solutions to ensure that network analysis and biological understanding remain connected are provided.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2008
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