Revealing the world of RNA interference
Article Abstract:
RNA interference (RNAi) is used as a research tool to control the expression of specific genes in numerous experimental organisms and has potential as a therapeutic strategy to reduce the expression of problem genes. The world of RNAi is introduced and an insight is provided that deals with a process that reflects an RNA world that is alive and thriving within human cells.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
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Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks
Article Abstract:
An integrated computational-experimental approach for computing the likelihood that gene products and associated pathways are targets of a compound is described. This was carried out by filtering the mRNA expression profile of compound-exposed cells using a reverse-engineered model of the cell's gene regulatory network.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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A green light to expression in time and space
Article Abstract:
The article analyzes the genome-scale in worms wherein Green Fluorescent protein (GFP) reporter constructs are developed in C. elegans. This gives information on the temporal and spatial gene expressions.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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