Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes
Article Abstract:
The conformational behavior of DNA chains after thermal melting in the presence of a cationic surfactant at different concentrations was investigated by means of combined calorimetric and dynamic light-scattering measurements. It was found that although the surfactant-free DNA form undergoes the usual thermal stability, the surfactant-saturated DNA from assumes a rather compact globular conformation and presents a very high thermal stability.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2006
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Polymorphism of DNA/Multi-cationic lipid complexes driven by temperature and salts
Article Abstract:
A study was done on the structural polymorphism of DNA/lipopolyamine (multi-cationic lipid) complexes by using X-ray diffraction and cryo-electron microscopy. The series of experiments reported show that the polymorphism of the DNA lipid complexes is driven by the initial state of the cationic lipid.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2001
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Conformation change of poly(dG-dC).(dG-dC) in cationic polyamine liposome complexes: effect of charge density and flexibility of amine chains in headgroups
Article Abstract:
Transfection mechanisms can be understood by identifying DNA conformation in delivery cargoes. Systematic studies of DNA conformations in various cationic liposome complexes may help developing improved gene delivery systems.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2000
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