Acute-phase protein synthesis in rats is influenced by alterations in plasma and muscle free amino acid pools related to lower plasma volume following trauma

Article Abstract:

A link exists between the protein pool of uninjured skeletal muscle and acute-phase protein (APP) synthesis. This was concluded following an examination of experimental data which indicate that APP synthesis in rats is affected by changes in the muscle and plasma amino acid pools. The latter, in turn, depends on the extent of the reduction on the plasma volume following trauma. The effect of plasma volume on protein turnover in skeletal muscle and liver affirms the cellular hydration state's 'second messenger' role in protein synthesis control in muscle and liver cells.

Research, Physiological aspects, Wounds and injuries, Injuries, Protein synthesis, Blood plasma

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Human amino acid requirements

Article Abstract:

Nutritional science has long been concerned with discovering the benefits, or the lack of such, of proteins in the human diet. Although scoring patterns that determine the value of plant-based diets in human nutrition have been proposed by the Food and Agriculture Organization/World Health Organization/UN University, and the Massachusetts Institute of Technology, the significance of proteins in the human diet can be better understood by analyzing the adaptive responses of human amino acid and protein metabolism to changes in intakes.

Health aspects

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