Dietary fat and cholesterol modulate the plasma lipoprotein distribution and production of pigment or cholesterol gallstones in hamsters

Article Abstract:

The influence of diet on plasma lipoprotein levels and gallstone induction in hamsters was studied. Male Syrian hamsters were fed diets containing fat or cholesterol with glucose or lactose and fat-free diets with or without fiber. Diets containing glucose or lactose, fiber and minimal essential fatty acids induced the formation of pigment gallstones typical of normal lipoprotein levels. The low fat diet containing cholesterol and limited in essential fatty acids induced cholesterol gallstones, usually associated with high very low density lipoprotein levels.

Health aspects, Gallstones, Dietary fat, Lipoproteins, Blood lipoproteins, Hamsters

---

Dietary saturated fatty acids and LDL receptor activity

Article Abstract:

Alternative intrepretations are offered on a study conducted by Stucchi, Terpstra and Nicolosi on dietary saturated fatty acids and low density lipoprotein receptor activity. In the study, cynomolgus monkeys were fed purified diets containing 48-60 mg. cholesterol/MJ, substantially increasing total plasma cholesterol. However, the results are more in keeping with the cholesterol sensitivity of cynomolgus monkeys than with the effect of specific saturated fatty acids on the modulation of cholesterol metabolism.

---

Dietary saturated fatty acids and LDL receptor activity: a response to Hayes and Khosla

Article Abstract:

The comments of Drs. Hayes and Khosla on a report on the relationship between dietary saturated fatty acids and low density lipoprotein metabolism in cynomolgus monkeys are well appreciated. The alternative interpretations are supported by data and can be considered as viable additions to the report. However, it should be noted that these alternative interpretations came about because of the disparity of plasma lipids at varying dietary cholesterol intakes among published researches.

Similar abstracts:

• Abstracts: Hyperresponsiveness to dietary cholesterol in inbred rabbits is not associated with enhanced reduction in binding of beta-VLDL to liver membranes
• Abstracts: Miami: a garden of cultural and culinary delights. Tasmania: rugged shores and orchards of plenty. Christmas in Montreal
• Abstracts: Viva Las Vegas! With casinos, shopping, and a new crop of trendy restaurants, a desert town becomes a hedonist's delight
• Abstracts: Beta-carotene increases lung cancer incidence in cigarette smokers. Retinoic acid response elements as positive and negative regulators of the expression of the Homeobox b-1 gene
• Abstracts: 30-minute main courses. part 16

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.