Metabolism of nitrogenous compounds by ruminant liver
Article Abstract:
Ruminants take in considerable amounts of nitrogen in the form of ammonia, which is absorbed and converted to urea in the liver. Rising nitrogen intake causes an increase in both ammonia and urea production. This is associated with an increase in the liver clearance of amino acids. The cause of this association is undetermined, but the utilization of aspartate or glutamate in ureagenesis and its connection to other liver functions are implicated. Amino acids are also potential sources of carbon for glucose synthesis, therefore, gluconeogenesis may also contribute to the amino acid clearance rate of the liver.
Publication Name: The Journal of Nutrition
Subject: Food/cooking/nutrition
ISSN: 0022-3166
Year: 1992
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Cytochrome b5/cytochrome b5 reductase complex in rat liver microsomes has NADH-linked aquacobalamin reductase activity
Article Abstract:
Rat liver microsomal NADH-linked aquacobalamin reductase was characterized to elucidate its possible physiological role. Elution profiles of the solubilized enzyme showed that NADH-linked aquacobalamin reductase activity is derived from the cytochrome b5/cytochrome b5 reductase complex. This finding was further confirmed by enzyme activity and inhibition experiments. These results demonstrate that a microsomal electron transfer protein also mediates the synthesis of cobalamin coenzymes.
Publication Name: The Journal of Nutrition
Subject: Food/cooking/nutrition
ISSN: 0022-3166
Year: 1992
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Comparative metabolism of phylloquinone and menaquinone-9 in rat liver
Article Abstract:
Vitamin K requirement can be satisfied either by phylloquinone or manaquinones (MK), obtained from plants and intestinal microflora, respectively. The turnover of phylloquinone and MK-9 in rat liver was determined and their efficiencies in satisfying vitamin K requirement were assessed. The results showed that the turnover of MK-9 is much slower than that of phylloquinones. In addition, phylloquinones have a generally higher biological activity than MK-9.
Publication Name: The Journal of Nutrition
Subject: Food/cooking/nutrition
ISSN: 0022-3166
Year: 1992
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