Will an increased dietary folate intake reduce the incidence of cardiovascular disease?

Article Abstract:

Dietary supplementation with folic acid may not reduce mortality from coronary artery disease (CAD). Although homocysteine remythelation due to low dietary folate consumption is associated with CAD, folate has not been firmly established as the cause of CAD. Estimates of preventing 50,000 CAD-related deaths per year after fortifying food with folate may not be correct because they are based on statistical modeling that cannot account for all the complexities of life-long dietary patterns and the risk factors in CAD.

Cardiovascular diseases, Prevention, Enriched foods, Atherosclerosis

---

Homocysteine - an atherogenic and a thrombogenic factor?

Article Abstract:

New studies suggest that hyperhomocysteinemia increases the risk for coronary heart disease, the leading cause of death in Western countries. Based on patients suffering from hyperhomocysteinemia, it was observed that an elevated level of homocysteine is a risk factor for vascular disease. Other studies also support that hyperhomocysteinemia is a risk factor for venous thrombosis. These evidences suggest that an elevated homocysteine is both atherogenic and thrombogenic.

Development and progression, Coronary heart disease, Thrombosis, Deep vein, Deep vein thrombosis, Arteries, Arterial stenosis

---

Is an elevated circulating material homocysteine concentration a risk factor for neural tube defects?

Article Abstract:

Mothers who suffer from neural tube defect neonates have higher circulating homocysteine concentrations compared with controls which shows impaired homocysteine remethylation resulting in a probable methionine shortage at a an important stage of fetal development. The study suggests a combined use of vitamin B-12-folic acid supplement rather than folic acid to check neural tube defects.

Research, Analysis, Abnormalities, Neural tube, Neural tube defects, Homocystinuria

Similar abstracts:

• Abstracts: Beta-carotene increases lung cancer incidence in cigarette smokers. Retinoic acid response elements as positive and negative regulators of the expression of the Homeobox b-1 gene
• Abstracts: Lowered energy intake and dietary macronutrient balance: potential consequences for micronutrient status. Low-fat, high-carbohydrate diets and atherogenetic risk
• Abstracts: Chile: a new golden age. Chinon: red wine from the garden of France. Italy's Adige Valley
• Abstracts: The nutrition transition: new trends in the global diet. Behavioral and social influences on food choice. Intense sweeteners and the control of appetite
• Abstracts: Dinner from the garden. A casual wine-tasting dinner. Thanksgiving on the farm

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.