Treatment of uncomplicated urinary tract infection with temafloxacin
Article Abstract:
Temafloxacin is a new type of antibiotic of the fluoroquinolone group. It has strong antimicrobial activity against a wide variety of bacteria and is well tolerated by the body, causing few adverse side effects. The effectiveness of temafloxacin in treating uncomplicated urinary tract infection was assessed and compared with several control drugs known to be effective in treating these infections. The control treatments consisted of trimethoprim/sulfamethoxazole, ciprofloxacin and norfloxacin. A total of 555 women with signs anf symptoms of urinary tract infection, such as fever (over 100 degrees F.), painful urination, frequency, urgency and hematuria (blood in the urine). The women were treated with temafloxacin or one of the control agents. The clinical symptoms of urinary tract infection were alleviated in 99 percent (305 of 308) patients who were treated with temafloxacin, compared with 100 percent (247 of 247) of those treated with the control drugs. Complete eradication of bacteria occurred in 99 percent (289 of 292) of the temafloxacin group and 97 percent (237 of 245) of the control group. Adverse side effects were experienced by a small percentage of the patients. Nausea was experienced by 3.5 percent of those treated with temafloxacin and 6.6 percent of those treated one of the control drugs. Headache was experienced by 5.4 percent of the temafloxacin-treated women and 3.4 percent of those treated with a control drug. These results show that temafloxacin is an effective treatment for women with uncomplicated urinary tract infection. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: American Journal of Medicine
Subject: Health care industry
ISSN: 0002-9343
Year: 1991
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Current concepts in the treatment of urinary tract infections and prostatitis
Article Abstract:
Infection of the urinary tract frequently occurs in women between 20 and 40 years. Urinary tract infections are most commonly caused by the bacteria Escherichia coli, although other types of bacteria can cause disease. These infections are treated with antibiotics if the symptoms are typical of bacterial infection and bacteria are present in the urine. Various types of antibiotics are used to treat urinary tract infections, including the new type of antibiotic known as the fluoroquinolones. Fluoroquinolones are very effective in killing a wide range of bacteria. They are tolerated well by patients with minimum side effects. Bacteria have been essentially unable to develop resistance to these antibiotics and, consequently, they remain an effective treatment. Resistance to other antibiotics has occurred among some the bacteria that cause urinary tract infections. Fluoroquinolones are very effective in treating these infections because they are able to penetrate into the urinary tract and are found in high concentrations in the urine. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: American Journal of Medicine
Subject: Health care industry
ISSN: 0002-9343
Year: 1991
User Contributions:
Comment about this article or add new information about this topic: