A 16-year-old boy with recurrent abdominal pain
Article Abstract:
A 16-year-old boy was admitted to a hospital with recurring abdominal pain. He had suffered from recurring abdominal pain since the age of four. His parents were originally from Turkey and his older brother also suffered from abdominal pain. An abdominal X-ray showed intestinal blockage and other symptoms led his doctors to consider familial Mediterranean fever. This genetic disorder affects Jews, Arabs, Turks and Armenians. The gene mutation results in an abnormal protein in immune cells called neutrophils. The end result is an abnormal activation of the inflammatory response. The patient and his family declined treatment.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
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A 13-year-old boy with genital edema and abdominal pain
Article Abstract:
A 13-year-old boy was admitted to a hospital with abdominal pain and swelling of the penis and scrotum. A CT scan of his abdomen was unable to find anything that could cause the genital swelling. However, a biopsy of his scrotum showed abnormalities called granulomas. Imaging of the gastrointestinal tract showed evidence of inflammatory bowel disease. He was diagnosed with Crohn's disease that had spread to his genitals.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
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A 47-year-old woman with diabetes, Crohn's colitis, and a painful swelling of the foot
Article Abstract:
A 45-year-old woman with a history of type 2 diabetes and a painful, swollen foot was diagnosed with pyoderma gangrenosum caused by Crohn's disease. Pyoderma gangrenosum is a skin disease that is commonly associated with inflammatory bowel disease.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
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