A vaccine against rotavirus - when is too much too much?

Article Abstract:

A vaccine against rotavirus has been developed and tested but it may be too expensive for those countries that need it most. Rotavirus is a common cause of diarrhea in young children, especially in developing countries. The vaccine has been tested in the US and Venezuela, where it protected about 80% of the children from rotavirus-induced diarrhea. However, the vaccine was less effective when tested in Peru and Brazil, where poorer sanitary conditions may prevail. However, these conditions are precisely those that lead to rotavirus infections. The vaccine is also too expensive for many developing countries.

Editorial, Economic aspects, Prevention, Developing countries, Rotavirus infections, Diarrhea in children, Childhood diarrhea, Viral vaccines

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Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: A randomized controlled study

Article Abstract:

The effectiveness on symptoms, beliefs, and behavior of 3 different antibiotic prescribing strategies are assessed with an additional information leaflet for acute lower respiratory tract infection. The findings suggested that in the patients with acute uncomplicated lower respiratory tract infection, the use of delayed antibiotics or no antibiotics, resulted in little difference in duration or severity of symptoms compared with immediate treatment with antibiotics.

United States, Antibiotics, Clinical trials

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Vitamin E and respiratory tract infections in elderly nursing home residents

Article Abstract:

Vitamin E supplementation on respiratory tract infections in elderly nursing home residents is studied. The test show that supplementation with 200 IU per day of vitamin E did not have significant effect on lower respiratory tract infections in elderly nursing home residents, but a protective effect of vitamin E supplementation on upper respiratory tract infections, particularly the common cold, merits further investigation.

Vitamin E, Dosage and administration, Aged patients, Elderly patients

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