Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study

Article Abstract:

Schizophrenics have less gray matter in the left temporal lobe of the brain than do normal people. Patients had a decrease in the volume of gray matter in the anterior hippocampus-amygdala, parahippocampal gyrus and an increase in the volume of the temporal horn of the lateral ventricles on the left side. The severity of disease was related to the decrease in volume of the left posterior superior temporal gyrus. This area is important as a neurological substrate of language. There was also a smaller volume in temporal-lobe regions which are connected neurologically and form auditory associative memory links. The schizophrenics and normal men in the study did not differ significantly in height, weight, head circumference, family socioeconomic status or intelligence.

Abnormalities, Physiological aspects, Schizophrenia, Temporal lobes

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A 50-year-old woman with multiple sclerosis and an enlarging frontal-lobe mass

Article Abstract:

A 50-year-old woman was admitted to a hospital for evaluation of a slow-growing mass in her brain. She had a history of multiple sclerosis and began having headaches 15 years before admission. Upon admission, an MRI scan revealed a mass in the right frontal lobe of her brain that had been present six years before. During brain surgery, part of her right frontal lobe was removed and microscopic examination revealed it to be a type of tumor called an oligodendroglioma.

Diagnosis, Gliomas, Brain tumors

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A randomized, controlled trial of surgery for temporal-lobe epilepsy

Article Abstract:

Surgery appears to be more effective than drugs for treating temporal lobe epilepsy. In a study of 80 patients who had one or the other treatment, 58% of the surgery patients were free of seizures that impaired their awareness one year later, compared to 8% of the patients who took anticonvulsants.

Surgery, Temporal lobe epilepsy

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