The potential role of magnetic resonance imaging in ischemic vascular disease

Article Abstract:

Magnetic resonance imaging (MRI) may be a valuable tool for the evaluation of patients with vascular disease. Flowing blood produces a unique signal during MR that enables visualization of the vascular system without the use of contrast medium. This use of MRI is referred to as MR angiography. This technique has not been widely used to diagnose ischemic cardiovascular disease because it has several shortcomings. A research study found that MR angiography provided more information than contrast x-ray angiography in evaluating patients with ischemic peripheral vascular disease. Other researchers have reported that MR angiography is an effective method for evaluating obstructive vascular disease in the carotid artery and the kidneys. It may also be a valuable technique for the assessment of vascular function. The future of MRI in the evaluation of ischemic cardiovascular disease is uncertain. It may be used in combination with x-ray angiography to provide additional diagnostic information.

Editorial

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Magnetic resonance imaging of angiographically occult runoff vessels in peripheral arterial occlusive disease

Article Abstract:

Magnetic resonance (MR) angiography may be a safer and more effective method than contrast arteriography for imaging blocked blood vessels in the limbs of patients with peripheral arterial disease. Patients with blocked vessels often undergo bypass surgery in which blood vessels are grafted to restore the blood supply to their limb. Both MR angiography and contrast arteriography were used to image lower-leg blood vessels of 23 patients (25 legs) with peripheral arteriosclerosis a blocked blood vessel. Contrast arteriography did not detect 22 blood vessels that were detected by MR angiography, but MR angiography detected all those detected by contrast arteriography. Detection of additional blood vessels using MR angiography changed the surgery plan used for four patients (17%). Bypass surgery was successful in all four patients. MR angiography is less invasive and safer than contrast arteriography, which involves the injection of a dye into the blood vessels.

Care and treatment, Arterial occlusions, Arterial occlusive diseases

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Lack of association between antimyelin antibodies and progression to multiple sclerosis

Article Abstract:

A study measured anti-myelin oligodendrocyte glycoprotein (MOG) and anti-myelin basic protein (MBP) antibodies in patients with a first clinical event suggestive of multiple sclerosis and at least two clinically silent lesions on brain magnetic resonance imaging (MRI). Results show that serum antibodies against MOG and MBP are not associated with an increased risk of progression to clinically definite multiple sclerosis in patients who had a clinically isolated syndrome suggestive of the disease.

Development and progression, Drug therapy, Multiple sclerosis, Disease/Disorder overview

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