Acquired von Willebrand syndrome in aortic stenosis

Article Abstract:

Aortic stenosis can cause excessive bleeding by damaging proteins involved in blood clotting, according to a study of 50 patients. In patients with aortic valve stenosis, the aortic valve in the heart is narrower than normal. This damages a large blood clotting protein called von Willebrand factor as it passes through the valve and this in turn causes excessive bleeding. This explains why blood clotting returns to normal in many patients who have the valve replaced with an artificial valve.

Von Willebrand's disease

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Aortic stenosis, von Willebrand factor, and bleeding

Article Abstract:

A heart valve disorder called aortic stenosis can cause excessive bleeding because it damages a large blood clotting protein called von Willebrand factor. Patients with aortic stenosis have an aortic valve that does not close properly. This causes increased blood flow through the valve that damages von Willebrand factor. The only way to stop the bleeding is to replace the valve.

Von Willebrand factor

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Prevention and treatment of major blood loss

Article Abstract:

Surgery is the major cause of blood loss in medical settings. Prevention and treatment of the same is discussed.

Care and treatment, Prevention, Clinical report

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