Advances in H1-antihistamines
Article Abstract:
The differences in the clinical pharmacology and the similarities in efficacy and safety of the H1-antihistamines are reviewed for elaborating its role in neurotransmission,rengland c inflammation, and immune modulation. It is concluded that most H1-antihistamines have similar efficacy in allergic rhinoconjunctivitis and chronic urticaria, however, there are clinically relevant differences in their pharmacologic characteristics and their safety profiles.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
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The preventive polypill - Much promise, insufficient evidence
Article Abstract:
Poor adherence to multidrug regimens is a common difficulty in effective therapy, but some observers believe this problem can be overcome through the 'polypill', which is a single pill that would include several key drugs. Although the concept of the polypill shows much promise, more clinical trials need to be conducted to provide evidence on the cost-effectiveness, safety, and adherence profile of the combination pill.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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Hepatocellular Carcinoma and sex
Article Abstract:
The article discusses a mouse based research that revealed estrogen countered pathway that provides insight into difference in prevalence of hepatocellular carcinoma between the sexes is reported.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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