Airway smooth muscle in asthma - not just more of the same

Article Abstract:

In culture, serum or bronchoalveolar-lavage fluid patients with asthma causes greater proliferation of human airway smooth-muscle cell than does serum or lavage fluid from normal subjects. It is conceivable that the same intrinsic difference between asthmatic and normal smooth muscle accounts for both the increases in proliferation and the altered contractility.

Risk factors, Cell proliferation, Smooth muscle

---

Evidence of a role of tumor necrosis factor alpha in refractory asthma

Article Abstract:

The markers of tumor necrosis factor alpha (TNF-alpha) activity on peripheral-blood monocytes in 10 patients with refractory asthma, 10 patients with mid-to moderate asthma, and 10 control subjects are measured. It is concluded that patients with refractory asthma have evidence of up-regulation of the TNF-alpha axis.

England, Health aspects, Tumor necrosis factor, Tumour necrosis factor

---

Chitin checking-novel insights into asthma

Article Abstract:

A study conducted by experts provides insight into the pathogenesis of allergic asthma that could fuel the development of new therapies. Chitin, a carbohydrate polymer, is found in allergic airway responses and it is observed that the enzyme is critical to disease expression in an experimental model of asthma.

Drug therapy, Allergy, Allergic reaction

Similar abstracts:

• Abstracts: Depression and mortality in nursing homes. Probing the meaning of racial/ethnic group comparisons in crack cocaine smoking
• Abstracts: Termination of pregnancy. The evidence base for using preoperative antiseptics. An assessment of the clinical effectiveness of surgical drapes
• Abstracts: A systematic review of the clinical significance of pulmonary mycobacterium kansasii isolates in HIV infection
• Abstracts: Mild persistent asthma: traits, treatment set it apart from mild intermittent asthma. Managing asthma during pregnancy: the whys and hows of aggressive control
• Abstracts: Quantitative magnetic resonance imaging of the knee: a method of measuring response to intra-articular treatments

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.