Altered apoptosis levels in hearts of human fetuses with Down syndrome

Article Abstract:

Fetal hearts with Down syndrome may have a lower than normal rate of apoptosis, a type of programmed cell death. Apoptosis is a regular feature of fetal development without undue injury to the affected organ. Compared to five hearts without any abnormalities (controls), researchers found lower instances of apoptosis in 15 hearts with Down syndrome. It is unclear how lower rates of apoptosis relate to the risk of heart abnormalities in Down syndrome.

Abnormalities, Physiological aspects, Cell death, Down syndrome, Fetal heart

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Alloimmune thrombocytopenia: State of the art 2006

Article Abstract:

Maternal immunoglobulin G anti-platelet alloantibodies cross the placenta and cause fetal thrombocytopenia in cases of alloimmune thrombocytopenia (AIT). The diagnosis requires laboratory demonstration of incompatibility between a maternal and paternal platelet alloantigen, and detection of material antibody to the discordant paternal allonatigen.

United States, Health aspects, Diagnosis, Causes of, Pregnant women, Thrombocytopenia

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Are women who are Jehovah's Witnesses at risk of maternal death?

Article Abstract:

The rate of death from postpartum hemorrhage among female Jehovah's Witnesses is 44 times greater than in the general population, according to a study of 332 women. Jehovah's Witnesses refuse blood transfusions but these women can be treated with a hysterectomy if necessary.

Patient outcomes, Mortality, Women, Hemorrhage, Puerperal disorders

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