Aneurysm treatments expand

Article Abstract:

Abdominal aortic aneurysms (AAAs) are caused by pathological changes in the aortic wall that lead to segmental weakening, progressive dilation and spontaneous rupture. Pharmacologic therapy may prevent further deterioration of the aortic wall in individuals with small AAAs as anti-inflammatory agents and proteinase inhibitors not only suppress development of aneurysms but also induce regression.

Antiinflammatory Drugs, Care and treatment, Usage, Anti-inflammatory drugs, Anti-inflammatory agents, Pharmacology, Abdominal aneurysm, Abdominal aortic aneurysm

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Cocaine's long run

Article Abstract:

Locomotor activity in response to cocaine increases with repeated administration. A microarray-based strategy is presented that yield clues to the basis for this heightened sensitivity.

Central Nervous System Prep, Cocaine, Central nervous system agents

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Cocaine addiction therapy -- are we partially there?

Article Abstract:

A selective dopamine D-3 receptor partial agonist reduces the craving for cocaine in a mouse model. The compound, BP 897, has no addictive properties itself.

Drug therapy, Cocaine abuse, Dopamine, Dopamine agonists

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