Anti-infective antibodies: Finding the path forward
Article Abstract:
Basel-based Novartis Pharmaceuticals, in its quest to find new weapons to fight infections, has paid $569 million to acquire NeuTec Pharmaceuticals of Manchester, UK, and its two late-stage products, both antibody fragments developed as therapies for difficult-to-treat microbes. NeuTec's anti-staph product, Aurograb is an antibody fragment mAb rather than a polyclonal antibody and binds to the staphylococcal ABC transporter, a drug-efflux pump and if Aurograb is successful it might boost more than Novartis's profit.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
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Survey finds 136 medicines in testing for infectious diseases
Article Abstract:
A new survey conducted by the Pharmaceutical Research and Manufacturers of America (PhRMA) has revealed that 136 new medicines against infectious diseases are being tested by pharmaceutical and biotechnology firms. PhRMA Pres Alan F. Holmer said these medicines and vaccines undergoing clinical trials represent hope for reducing the threat posed by infectious diseases, which are the world's leading cause of death. Medicines under development include 42 vaccines, 27 antibiotics and 31 antivirals.
Publication Name: Vaccine Weekly
Subject: Health
ISSN: 1074-2921
Year: 1998
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Letting antibodies get to your head
Article Abstract:
The disaster caused by streptococcal sugar in Sydenhum chorea is illustrated. The cross-reaction of antibodies was elevated in sera and cerebrospinal fluid during acute Sydenhum chorea.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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