Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging

Article Abstract:

Artificial engineering approaches are used to develop innovative magnetic nanoprobes via a process involving the systematic evaluation of the magnetic spin, size and type of spinel metal ferrites. The magnetism-engineered iron oxide (MEIO) nanoprobes are used to visualize small tumors implanted in a mouse and they can also enhance the ability to visualize other biological events critical to diagnostics and therapeutics.

Diagnostic imaging, Ferrites (Magnetic materials), Nanoparticles

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Integrin alphavbeta3 is a coreceptor for human cytomegalovirus

Article Abstract:

A study demonstrates that human cytomegalovirus (HCMV) uses integrin alphavbeta3 as a coreceptor. The findings support a model in which epidermal growth factor receptor (EGFR) and alphavbeta3 work together as conceptors for HCMV entry and signaling. This discovery is fundamental to understanding JCMV pathogenesis and developing treatment strategies targeted to viral receptors.

United States, Health aspects, Usage, Risk factors, Integrins, Cytomegaloviruses, Cytomegalovirus, Epidermal growth factor receptors, Immunocompromised host

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A new transgene reporter for in vivo magnetic resonance imaging

Article Abstract:

A new platform technology for visualizing trangene expression in living subjects using magnetic resonance imaging (MRI) is reported. Following focal inoculation of the vector into the mouse brain, the reporter activity is monitored using in vivo time-lapse MRI.

Magnetic resonance imaging, Immunization

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