Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
Article Abstract:
A study to ascertain if the development of systemic lupus erythematosus (SLE) is influenced by the presence of certain genes is conducted. Results confirm that the hereditary genes play a role in the development as also reduced expression of BLK and increase depression of C8orf13 and variants in the ITGAM-ITGAX region.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2008
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STAT4 and the risk of rheumatoid arthritis and systematic lupus erythematosus
Article Abstract:
The single-necleotide polymorphism was tested within the previously linked chromosome region for association with rheumatoid arthritis. Results showed that the halotype STAT4 was associated with increased risk of both rheumatoid arthritis and systematic lupus erythematosus.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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TRAF1-C5 as a risk locus for rheumatoid arthritis- a genomewide study
Article Abstract:
The article discusses a study that helps in the identification of several genetic loci, including TRAF1 (encoding tumor necrosis factor-receptor associated factor 1) and C5 (encoding complement component 5) that increase the risk for rheumatoid arthritis considerably.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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