Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine
Article Abstract:
An international, randomized clinical trial was conducted to examine the effect BIBN 4096 BS on 126 patients with migraine after they received it intravenously over a period of ten minutes. The results showed that the Calcitonin gene-related peptide (CGRP) antagonist BIBN 4096 BS was effective in treating acute attacks of migraine.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
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NXY-059 for acute ischemic stroke
Article Abstract:
NXY-059, a free-radical-trapping agent that is neuroprotective in animal models of stroke is tested on humans to see if it would reduce disability after acute ischemic stroke. The results show a benefit in terms of the prespecified primary end point, a reduction in disability as measured by the modified Rankin score at 90 days.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
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NXY-059 for the treatment of acute ischemic stroke
Article Abstract:
The efficacy of the free-radical-trapping agent NXY-059 as a neuroprotectant is assessed in the Stroke-Acute Ischemic NXY Treatment II (SAINT II) trial. The results have shown that NXY-059 is safe but ineffective for the treatment of acute ischemic stroke within 6 hours after the onset of symptoms.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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