Candida tropicalis chorioamnionitis

Article Abstract:

Fetal candida infections are rare, but are more likely to occur with the presence of an IUD. Candida is a type of yeast. At 25 weeks gestation a woman presented with general malaise and intermittent abdominal pain. She had conceived with an IUD in place. Ultrasonography revealed a live fetus with a brain hemorrhage. Amniocentesis was performed and the fluid contained yeast, and cultures grew yeast. Two days later labor began, and a 760 g male was stillborn. Yeast filaments were found in his lungs, liver, and the placenta. Maternal vaginal and blood cultures were negative for Candida. The IUD was not found despite examination of the uterus and placenta at the time of the birth and X rays. The infection was Candida tropicalis, not C. albicans, a common cause of vaginitis in pregnancy. C. tropicalis occasionally is associated with abortion in cows, but never has been reported in humans. The patient was a veterinary nurse.

Diagnosis, Candidiasis, Chorioamnionitis

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Monozygotic twins discordant for single umbilical artery and congenital heart disease

Article Abstract:

A case report of two identical twins who had different congenital defects illustrates that identical twins can be affected differently by environmental factors. Identical twins originate from a single embryo and are normally genetically identical. When the twins were born, one was 20% heavier than the other. The lighter twin had a single right umbilical artery and was missing the left artery. However, this twin had no other congenital conditions. The heavier twin had several congenital heart conditions, including a patent ductus arteriosus and a septal defect.

Abnormalities, Congenital heart disease, Congenital heart defects, Umbilical arteries

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Biparental contribution to fetal thrombophilia in discordant twin intrauterine growth restriction

Article Abstract:

Doctors describe a twin pregnancy in which one twin inherited a gene mutation causing a blood clotting disorder from both its mother and father, whereas the other twin only inherited the gene from its mother. The first twin developed the blood clotting disorder but the second twin did not.

Fetus, Blood clotting disorders, Blood coagulation disorders, Fetal growth retardation

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