TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases

Article Abstract:

This article discusses autoimmune tissue and the molecular nature of its mediators in relation to rheumatoid arthritis and other autoimmune diseases. The study focuses on the mechanism of action of anti-TNF therapy and aspects of the pathogenesis of rheumatoid arthritis. Data show that C-reactive protein, serum amyloid A protein and haptoglobin are in the reduced state in rheumatoid arthritis.

Science & research, Physiological aspects, Influence, Rheumatoid arthritis, Inflammation mediators, Tumor necrosis factor, Immune response, Immune response regulation, Tumour necrosis factor

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Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

Article Abstract:

Issues related to the autoimmune disease myasthenia gravis, which affects neuromuscular junction, are examined, focusing on the role of auto-antibodies in the disease. Results indicate two distinct forms of the disease and the involvement of auto-antibodies against the muscle-specific receptor tyrosine kinase, MuSK.

Germany, Statistical Data Included, Myasthenia gravis

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Neuroprotective autoimmunity -- a double-edged sword?

Article Abstract:

A study in rats shows that antibodies against the NMDA glutamate receptor might prevent brain damage in stroke and seizures. However, the antibodies might attack other types of glutamate receptors and cause more harm than good.

Stroke (Disease), Stroke, Glutamate, Cell receptors

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