Carcinoma of the prostate
Article Abstract:
In the last decade, prostate cancer has become the most commonly diagnosed malignancy affecting men. More than 28,000 men - 11 percent of cancer deaths - die of the disease every year, making it the third leading cause of cancer death in men after lung and colon cancer. There does not seem to be any correlation between prostate cancer and diet, venereal disease, sexual habits, smoking, or exposure on the job. However, high testosterone levels have been proposed as a major determinant of the risk of prostatic cancer. Most tumors grow so slowly that they often go undetected. In asymptomatic patients, a yearly rectal examination after the age of 40 remains is important for identifying patients with prostatic cancer. Perhaps as many as 12,000 prostatic cancers are detected at a curable stage this way each year. Ultrasound imaging has the ability to detect growths as small as 5 mm in diameter. Treatment of early stage cancer is usually with radiation or removal of the prostate. In advanced stages, the cancer is treated with hormonal (antitestosterone) therapy. Stage IV, or metastatic, prostatic cancer is treated by more radical hormonal therapy and orchiectomy, surgical removal of the testicles to destroy testosterone production. Nonhormonal chemotherapy has not been useful in treating prostatic cancer. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1991
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Prostate cancer - the therapeutic challenge of locally advanced disease
Article Abstract:
Many patients with prostate cancer are confused about the various treatments and the debate between surgeons and radiotherapists has not helped. Radiation treatment was the treatment of choice in the past but surgical techniques have improved and men are being diagnosed at a younger age when the tumor is smaller. Several studies have evaluated radiation treatment plus drugs that block the production of male hormones. These drugs can shrink the tumor and delay disease progression but few studies have found improved overall survival rates.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
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Noninvasive detection of clinically occult lymph-node metastases in prostate cancer
Article Abstract:
Injecting small particles containing iron into patients with prostate cancer can improve the ability of MRI scans to detect metastatic cancer. These particles are taken up by lymph nodes and can be detected by MRI because they are magnetic. In a study of 80 patients with prostate cancer, this technique identified 45 cancerous lymph nodes that were not detected by traditional MRI scans.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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