Catheter-based radiotherapy to inhibit restenosis after coronary stenting

Article Abstract:

Radiotherapy delivered to the inside of the coronary arteries via a catheter appears to reduce the risk of restenosis in patients with coronary artery disease. Restenosis occurs when arteries that have been treated with angioplasty become blocked again. Researchers randomly assigned 55 patients to receive radiotherapy or no radiotherapy after they had angioplasty. An average of 6 months later, the patients treated with radiotherapy had wider arteries and only 17% experienced restenosis, compared to 54% of those who did not receive radiotherapy.

Methods, Radiotherapy, Transluminal angioplasty, Balloon angioplasty, Arteries, Arterial stenosis

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Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting

Article Abstract:

Gamma radiation therapy can prevent coronary arteries from becoming blocked again after angioplasty, according to a study of 252 patients. The radiation was delivered by a small radioactive source attached to a wire that was placed inside the artery. Patients with a small cylindrical device called a stent inside the artery were at risk of developing blood clots that could cause a heart attack.

Health aspects, Prevention, Gamma rays

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Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery

Article Abstract:

A stent that releases small amounts of the drug sirolimus over a period of time may reduce the chances that a patient's coronary arteries will become blocked again, according to a study of 1,058 patients. Some of these patients had diabetes, small coronary arteries, or more extensive atherosclerosis. Stents are small cylindrical devices that are placed inside arteries to keep the artery open.

Stent (Surgery), Stents, Sirolimus

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