Cervical dysplasia on cervicovaginal Papanicolaou smear among HIV-1-infected pregnant and nonpregnant women

Article Abstract:

The use of Pap smears to test a group of HIV-infected women, both pregnant and non-pregnant, showed a high incidence of low grade squamous intaepithelial lesions, but a low incidence the high grade variety. There were no cases of cervical cancer detected. In testing 426 nonpregnant and 126 pregnant HIV-infected women via Pap smear, these were the results, indicating that pregnancy may not be a factor in creating Pap smear abnormalities. However, the presence of squamous intraepithelial lesions raise a warning for closer examination and followup as it is associated with cervical inflammation, herpes simplex, and immunosuppression.

Testing, Women, Physiological aspects, HIV infections, HIV infection in women, Precancerous conditions, Pap test

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Assessment of birth defects according to maternal therapy among infants in the women and infants transmission study

Article Abstract:

A study was conducted to evaluate rate and types of birth defects according to timing of antiretroviral exposure among babies born to HIV-infected women. Only genital abnormalities, specifically hypospadias were significantly increased among babies born to women with first-trimester exposure to antiretroviral compared with the 2 other groups which called for further study related to first-trimester exposure.

Abnormalities, Diagnosis, Birth defects, Infants, HIV patients, Clinical report

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Improved obstetric outcomes and little maternal toxicity are associated with antiretroviral therapy, including highly active antiretroviral therapy during pregnancy

Article Abstract:

Data from 2543 HIV-infected women were analyzed to correlate antiretroviral therapy (ART) used during pregnancy with maternal and pregnancy outcomes. ART was analyzed according to class of agents used and according to monotherapy versus combination ART containing neither protease inhibitors nor nonnucleoside reverse transcriptase inhibitors versus highly active ART.

United States, Science & research, Research, Pregnant women, Protease inhibitors, Highly active antiretroviral therapy

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