Chlamydia pneumoniae infection and incident coronary heart disease: The Atherosclerosis Risk in Communities Study

Article Abstract:

A study has not found strong support for the hypothesis that Chlamydia pneumoniae, or Chlamydia TWAR, infection is a risk factor for clinical coronary heart disease (CHC). Data came from a case-cohort study involving participants in the Atherosclerosis Risk in Communities Study. The subjects were free of CHD at the baseline examination in 1986-89. Levels of C. pneumoniae immunoglobulin G (IgG) antibodies in serum collected at baseline from 246 incident cases of CHD found in follow-up were compared with those from a stratified sample of the baseline cohort, which numbered 550. More study is needed to see whether the infection is an etiologic factor in earlier atherogenesis.

United States, Social aspects, Statistical Data Included, Smoking, Pneumonia, Chlamydia infections, Epidemiology, Bacterial pneumonia

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Nontraditional Risk Factors for Coronary Heart Disease Incidence among Persons with Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study

Article Abstract:

Elevated blood levels of fibrinogen, factor VIII, von Willebrand factor and leukocyte count appear to be risk factors for coronary heart disease in diabetics. This was the conclusion of researchers who factored out all other traditional risk factors for coronary heart disease in a study of 1,676 diabetics with no history of heart disease. Over a nine-year follow-up, 186 diabetics had a heart attack or stroke. Hypertension, smoking, and elevated cholesterol levels were important risk factors, but so were fibrinogen, factor VIII, von Willebrand factor and leukocyte count.

Diabetes, Diabetes mellitus

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Plasma fatty acid composition and 6-year incidence of hypertension in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study

Article Abstract:

The composition of fatty acids as risk factors for hypertension in middle age is examined. Lower concentrations of both the ratio of polyunsaturated/saturated fatty acids and linoleic acid coupled with higher levels of palmitic and arachidonic acids represent a higher risk of hypertension.

Middle aged persons, Hypertension, Physiological aspects, Fatty acids, Atherosclerosis

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