Meta-analysis of the effects of soy protein intake on serum lipids

Article Abstract:

Consuming soy protein instead of animal protein may decrease blood cholesterol and other blood lipid levels. Data from 38 clinical studies were collectively analyzed. Eighty-nine percent of the studies reported a decrease in serum cholesterol levels in persons whose diet contained soy protein. The net reduction was 23 milligrams per deciliter. Similarly, 84% of studies reported a decrease in low-density-lipid (LDL) cholesterol, the "bad" cholesterol, with a net reduction of 22 milligrams per deciliter. Soy protein intake had little effect on those with normal or mildly elevated cholesterol levels. Those with moderately high values of 259 to 333 milligrams of cholesterol per deciliter had a 7% decrease and those with values greater than 333 milligrams had a 20% reduction. LDL-cholesterol reductions also varied according to initial LDL-cholesterol level. Soy protein intake of 25 g per day resulted in a decrease of 9 milligrams per deciliter of cholesterol whereas a 50 g intake resulted in a 17 milligram decrease and 75 g intake resulted in a 26 milligram decrease in cholesterol.

Health aspects, Care and treatment, Physiological aspects, Blood lipids, Hyperlipidemia, Hypercholesterolemia, Plant proteins, Soybean products

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Case 40-2006: A 64-year-old man with anemia and a low level of HDL cholesterol

Article Abstract:

A 64-year-old male was seen as an outpatient in the hematology division of a hospital because of anemia and a low serum level of high-density lipoprotein (HDL) cholesterol. Anatomical diagnosis suggests lymphoplasmacytic lymphoma with Waldenstrom's macroglobulinemia and biclonal gammopathy, while the falsely low serum HDL cholesterol result was due to the presence of a paraprotein.

Case studies, Anemia, High density lipoproteins, Case study

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