Chorionic villus sampling safety: report of World Health Organization/EURO meeting in association with the Seventh International Conference on Early Prenatal Diagnosis of Genetic Diseases, Tel-Aviv, Israel, May 21, 1994
Article Abstract:
A prenatal test known as chorionic villus sampling (CVS) may not cause birth defects in arms and legs when performed between weeks nine and 12 of pregnancy. Researchers evaluated the results of a CVS registry sponsored by the World Health Organization to determine whether CVS might cause the growth of limbs to be reduced in fetuses. A total of 138,996 patients were followed up after having a CVS. Seventy-nine infants or fetuses from this group were found to have limb defects. The ratio of 5.7 per 10,000 infants with limb defects to the entire group may be normal for a population. No one medical center was found to have a disproportionately high number of limb defects, and the types of limb defects were normal compared to the population at large. CVS may be as safe as amniocentesis when performed after eight weeks' gestation.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1996
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Prenatal paternity testing with deoxyribonucleic acid techniques
Article Abstract:
Prenatal paternity testing may be determined in the first trimester of pregnancy using DNA testing. Researchers performed prenatal paternity tests on 37 pregnant women, using 27 chorionic villus sampling specimens, eight amniocentesis specimens, and two products of conception. Paternity testing on the products of conception was conducted for law enforcement regarding two rape cases. DNA testing has increased the probability of exclusion of the wrong man's fatherhood to more than 99%. The latter 28 cases were successfully tested before delivery. First trimester testing may provide the mother with useful information before deciding to abort.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1996
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Obstetric outcomes in 102 pregnancies after preimplantation genetic diagnosis
Article Abstract:
Preimplantation genetic diagnosis seems to increase the risk of multiple pregnancy, cesarean section, and a placental abnormality called placenta previa. During preimplantation genetic diagnosis, the fertilized embryo is biopsied to collect a cell for genetic analysis.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
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