Chronic renal failure in non-insulin-dependent diabetes mellitus: a population-based study in Rochester, Minnesota

Article Abstract:

Previous studies have shown that the primary cause of renal (kidney) failure in the United States is diabetic nephropathy, kidney disease resulting from diabetes. Although insulin-dependent diabetes results in more deaths attributable to renal failure, many more individuals suffer from non-insulin dependent diabetes (NIDD). A large-scale study was performed using 2,022 white men and women who were diagnosed with chronic renal failure and proteinuria (protein in the urine, a symptom of kidney malfunction). All of these individuals, who had also been diagnosed with diabetes, were examined to identify the incidence of kidney failure by type of diabetes, and to investigate the relationship between persistent proteinuria and chronic renal failure in those with non-insulin-dependent diabetes mellitus. The results of this study indicated that individuals with NIDD represent the majority of cases of chronic renal failure among whites in this country. In addition, a strong correlation was observed between persistent proteinuria and the eventual development of chronic renal failure among individuals with NIDD. After adjustments in the data were made, it was found that when persistent proteinuria was observed at the time of diagnosis of NIDD, the risk of chronic renal failure was increased 12-fold. The risk of chronic renal failure increased by 11 percent when persistent proteinuria developed after the initial diagnosis of NIDD. The fact that most cases of chronic renal failure that are associated with diabetes occur in individuals with NIDD, along with the observed correlation of persistent proteinuria and the risk of kidney disease, may be useful in developing guidelines for preventive intervention method or treatments. (Consumer Summary produced by Reliance Medical Information, Inc.)

Case studies, Complications and side effects, Type 2 diabetes, Chronic kidney failure, Proteinuria

---

Expanding indications for permanent pacemakers

Article Abstract:

Implanting long-term pacemakers may be advisable for patients with hypertrophic obstructive and dilated heart diseases, long QT syndrome, for preventing atrial fibrillation, and in selected patients with nerve related fainting spells or following heart transplantation. Hypertrophic obstructive and dilated heart diseases affect blood flow and contractile heart function. Atrial fibrillation and the long QT syndrome produce irregular heart beats. Researchers summarized the current literature that documents the use of pacemakers in these forms of heart disease and in patients receiving heart transplants. One study showed significant improvement in 42 of 44 patients with hypertrophic obstructive heart disease who had pacemakers implanted. Another study showed that heart problems recurred in only 2 of 18 patients with long QT syndrome who took beta-blocking therapy and had pacemakers implanted. Pacemakers may only be necessary in patients receiving heart transplants if rhythm dysfunction continues longer than 3 weeks following transplant surgery.

Usage, Cardiac pacing

---

Survival and functional independence after implantation of a permanent pacemaker in octogenarians and nonagenarians: a population-based study

Article Abstract:

Permanent pacemakers do not seem to significantly improve the quality of life of many patients who receive them in their eighties and nineties. Researchers assessed independence characteristics and survival rates of 157 80-year-old and 90-year-old patients who received permanent pacemakers. Forty-five percent of these patients were placed in nursing homes. This is similar to national statistics for similarly aged people without heart disease. Survival rates were lower in these patients compared to national averages. Functional disability occurred in 26% of these patients, mental function deteriorated in 32%, but heart symptoms improved in 75%.

Health aspects, Social aspects, Aged, Elderly, Surveys, Quality of life

Similar abstracts:

• Abstracts: Barriers to care in non-insulin-dependent diabetes mellitus: the Michigan experience. Management of non-insulin-dependent diabetes mellitus: the United Kingdom experience
• Abstracts: Osteoarticular brucellosis in children. Vertebral hyperostosis and diabetes mellitus: a case-control study. Osteoarticular manifestations of pustulosis plamaris et plantaris and of psoriasis: two distinct entities
• Abstracts: The bonding evolution in dentistry continues. Evaluation of new products and concepts in dentistry. Destruction of human teeth
• Abstracts: A population-based serosurveillance of syphilis in Costa Rica. Laboratory diagnosis of sexually transmitted diseases in facilities within the United States: results of a national survey
• Abstracts: Emerging and re-emerging infectious diseases: a biological evolutionary drama. An update on HIV/AIDS

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.