Circulating vascular cell adhesion molecule-1 in pre-eclampsia, gestational hypertension, and normal pregnancy: evidence of selective dysregulation of of vascular cell adhesion molecule-1 homeostasis in pre-eclampsia
Article Abstract:
Blood levels of vascular cell adhesion molecule 1 appear to be elevated during pre-eclampsia. Pre-eclampsia is characterized primarily by high blood pressure during pregnancy. Researchers measured levels of vascular cell adhesion molecule 1 in blood samples from 22 pregnant women with pre-eclampsia, 13 pregnant women with chronic hypertension and 30 pregnant women with normal blood pressure. Women with pre-eclampsia had elevated levels of this molecule, which occurs on white blood cells and allows them to bind to other tissues. Levels were similar in the healthy women and those with chronic hypertension.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
Hemostasis in the uteroplacental and peripheral circulations in normotensive and pre-eclamptic pregnancies
Article Abstract:
Hemostasis appears to be altered in pregnant women with preeclampsia. Preeclampsia is characterized by high blood pressure during pregnancy. Researchers measured hemostasis in 42 pregnant women with preeclampsia and 49 healthy pregnant women by analyzing blood samples for the presence of chemicals produced during blood clotting and clot breakdown. Both processes were more active during pregnancy compared to the postpartum period. They were also more active in uterine blood vessels than in the general circulation. Women with preeclampsia had higher levels of clot breakdown than the healthy women.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
Serum from preeclamptic women induces vascular cell adhesion molecule-1 expression on human endothelial cells in vitro: a possible role of increased circulating levels of free fatty acids
Article Abstract:
Free fatty acids appear to play a role in activating the endothelium in preeclampsia. Preeclampsia is a condition of pregnancy characterized by hypertension and protein in the urine. Researchers exposed cultured endothelial cells to blood from healthy pregnant women and those with preeclampsia. Endothelial cells exposed to blood from preeclamptic women produced a chemical secreted during endothelial cell activation. Blood from preeclamptic women also had higher levels of fatty acids. Fatty acids are known to affect endothelial cells.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Diurnal enuresis in children. Limited evidence for treating nocturnal enuresis with complementary therapies. Effective treatment for children's enuresis: Childhood incidence of enuresis is distressingly high, and parents are often not able to deal with the problem on their own
- Abstracts: Recurrence risk of congenital anomalies - the impact of paternal, social, and environmental factors: a population-based study in Denmark
- Abstracts: Prevalence of rheumatoid arthritis and rheumatoid factor in women: evidence for secular decline. Genetics of osteoarthritis
- Abstracts: Scientific advances, societal trends, and the education and practice of obstetrician-gynecologists. Managed are: a ball control game