Contraindicated Use of Cisapride: Impact of Food and Drug Administration Regulatory Action

Article Abstract:

The use of the gastrointestinal drug cisapride did not change substantially after the FDA notified doctors in 1998 that the drug could cause arrhythmia in some patients. More effective methods are needed to disseminate this type of information to doctors.

Laws, regulations and rules, Causes of, Complications and side effects, Arrhythmia, United States. Food and Drug Administration, Cisapride

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Prescription drug use in pregnancy

Article Abstract:

Information is provided on the prevalence of the use of prescription drugs among pregnant women in the US. It was found that almost one half of all pregnant women received prescription drugs from categories C, D, or X of the US Food and Drug Administration risk classification system, which highlights the importance of the need to understand the effects of these medications on the developing fetus and on the pregnant women.

Drugs & Pharmaceuticals, Pharmaceutical and Medicine Manufacturing, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Drugs, Metabolic Agents NEC, Metabolic Agents, Health aspects, Surveys, Drug therapy, Pregnant women, Pregnancy

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Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs

Article Abstract:

A study is conducted to estimate the incidence of rhabdomyolsis in patients treated with different statins and fibrates along with the ambulatory setting. The results reveal that rhabdomyolsis risk is similar and low for monotherapy with atorvastatin, pravastatin and simvastatin and the combined statin-fibrate use increases risk in older patients with diabetes mellitus.

Care and treatment, Risk factors, Patients, Patient care, Rhabdomyolysis

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