Control of serum lipids with soy protein
Article Abstract:
Replacing dietary animal protein with soy protein appears to reduce triglyceride levels, overall cholesterol levels, and levels of low-density-lipoprotein cholesterol (LDL), the "bad" cholesterol, without affecting levels of high-density-lipoprotein cholesterol, the "good" cholesterol. Animal studies have repeatedly shown this effect, but individual dietary studies in humans have not been large enough. A group analysis of data from 38 clinical studies in humans achieved sufficient size: 740 participants. The analysis found that total cholesterol was reduced by 9%, LDL cholesterol by 13%, and triglycerides by 11%. The effect was more pronounced in individuals with higher initial cholesterol levels. Consuming soy protein is believed to be safe because many peoples have consumed it for centuries. Questions about how much should be consumed, its effects in various populations, and how it works in conjunction with other dietary fat-reducing strategies should be answered. Palatability is also an issue for populations not regularly eating soy-based foods.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1995
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Role of protein glycosylation in immune regulation
Article Abstract:
Protein glycosylation may play an important role in immune regulation. The process of protein glycosylation involves the attachment of sugars to specific sites on a protein molecule. Proteins that are on the surface of cells or that are secreted are usually glycosylated. The type of glycosylation is determined by the method in which the sugar is linked to the protein. The composition of the sugars attached to the proteins also varies. These sugars may be different sizes and may be composed of different types of subunits. Glycosylation of immune system proteins can regulate protein function and recognition. The sugars attached to these proteins may inhibit recognition and processing of the protein. Protein glycosylation may be involved in the development and progression of rheumatoid arthritis.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1993
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Regulation of firearms
Article Abstract:
It may be time to pass legislation to create safer guns and keep them out of the hands of criminals. Since the introduction of safer cars and highways, the number of vehicle-related fatalities has dropped more than 75% even though driver behavior probably has not changed. Similarly, creating safer guns could reduce the firearm-related injury rate. Safety measures include childproofing, indicators that show if the gun is loaded, and devices that prevent the gun from being used by an unauthorized person. National surveys indicate that most Americans support these concepts, even gun owners.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
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