Determination of interstitial collagenase (MMP-1) in patients with rheumatoid arthritis
Article Abstract:
The level of a protein substance in joint fluid known as MMP-1 may not be useful as an indicator of rheumatoid arthritis (RA) activity in the body, but it may be useful in indicating how much fluid inflammation there is in a specific joint. Researchers measured the amount of MMP-1 in joint fluid and blood samples from 41 patients with RA and found that MMP-1 levels did not reflect C reactive protein or MMP-1 levels in blood. MMP-1 levels in joint fluid did, however, correspond to the amount of joint fluid inflammation. Neither MMP-1 levels nor MMP-1 activity corresponded with levels of the tissue inhibitor of MMP. The release of MMPs into joint fluid causes cartilage to deteriorate, as happens in advanced RA.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
Circadian melatonin and cortisol levels in rheumatoid arthritis patients in winter time: a north and south Europe comparison
Article Abstract:
Circadian melatonin and cortisol levels in patients with rheumatoid arthritis during winter period in Estonia and Italy are compared.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
The development of the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas
Article Abstract:
The details on magnetic resonance imaging results to examine rheumatoid arthritis are examined.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Investigation of xerostomia in patients with rheumatoid arthritis. How can oral health care providers determine if patients have dry mouth?
- Abstracts: Demyelinating diseases - new pathological insights, new therapeutic targets. Molecular mimicry in multiple sclerosis
- Abstracts: Incidence of end-stage renal disease in patients with type 1 diabetes. Isolated pancreas transplantation for type 1 diabetes: a doctor's dilemma
- Abstracts: The prevalence of androgen excess among patients with minimal unwanted hair growth. Stress model for research into preterm delivery among black women
- Abstracts: The Determinanats of Participation in Activities of Daily Living in People with Impaired Vision. Microwave-superheated Vics Vapo Rub: An Ocular Public Health Danger